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Metronidazole (topical)

INCI: Metronidazole

Topical antibiotic from the nitroimidazole group. Doctors prescribe it for papulo-pustular rosacea and perioral dermatitis.

AcneSoothing

Evidence by route

Topical application

A

Proven efficacy. Two or more independent RCTs with instrumental endpoints.

Cochrane rosacea review places topical metronidazole in first-line therapy. Efficacy matches ivermectin and azelaic acid.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Caution

Frequently asked questions

Is Metronidazole (topical) safe during pregnancy?

Metronidazole (topical) should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.