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Piroctone Olamine

Second-generation antifungal agent, a zinc pyrithione replacement. Effective against Malassezia – the fungus causing dandruff and seborrheic dermatitis.

AcneSoothing

Evidence by route

Topical application

B

Limited evidence. One RCT or several controlled studies with limitations.

RCTs confirm efficacy for seborrheic dermatitis and dandruff comparable to ketoconazole. Included in medicated shampoos as a safe alternative to zinc pyrithione after its EU restriction.

  • Schmidt-Rose T et al. Int J Cosmet Sci. 2011;33(3):276-282.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

OilyCombinationNormal

Frequently asked questions

Is Piroctone Olamine safe during pregnancy?

Piroctone Olamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Piroctone Olamine for?

Piroctone Olamine suits: oily, combination, normal.

Piroctone Olamine – what it is, how it works, who it's for – Evigrade