Evigrade

Saccharomyces Ferment Filtrate

Yeast fermentation product containing amino acids, vitamins, and minerals. The core ingredient in SK-II Pitera. Moisturizes and evens skin texture.

Evidence by route

B

Topical application

Small clinical studies (mostly industry-sponsored) show texture improvement, hydration, and pigmentation lightening. Filtrate composition standardization is difficult. No independent rigorous RCTs.

  • Hsu S. J Am Acad Dermatol. 2005;53(6):1073-1075. PMID 15928624
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily
Use with caution
Sensitive

About this ingredient

Saccharomyces Ferment Filtrate is a fermentation product of food yeast Saccharomyces cerevisiae or related strains. Contains amino acids, oligopeptides, B-vitamins (B1, B2, B3, B5, B6, B9, B12), minerals (zinc, copper, selenium), β-glucans, nucleotides. In global cosmetics known through the legendary SK-II Pitera ingredient (Pitera is actually galactomyces, but commercial saccharomyces filtrates work analogously). Where applied. Essence toners, serums and creams of Asian origin (5-50%), brightening lines, mature-skin products, recovery masks. In Spain on shelves of Sesderma Azelac Ru, certain SK-II analogues in large department stores (El Corte Inglés). Evidence base. Bissett 2006 (n=43, 8 weeks) showed improved facial skin texture, tone and elasticity after using a toner with 90% Pitera. Lim 2014 in atopic patients – reduced TEWL and improved barrier. Evidence for specific commercial Pitera (galactomyces) is stronger than for general saccharomyces filtrate; evidence quality for individual saccharomyces filtrates – B/C. Mechanism. β-glucans stimulate collagen synthesis in fibroblast cultures and activate skin innate immunity. Amino acids and B-vitamins work as cofactors of cellular metabolism. The effect is complex, not reducible to one compound. Safety. CIR confirmed safety of saccharomyces filtrates in cosmetics (Final Report 2015). Hypoallergenic for most users. People with yeast allergy (rare) or yeast-based irritable bowel syndrome – use with caution. Pregnancy and lactation – safe. Food yeast, natural origin, no systemic absorption. No restrictions.

Frequently asked questions

Is Saccharomyces Ferment Filtrate safe during pregnancy?

Saccharomyces Ferment Filtrate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Saccharomyces Ferment Filtrate for?

Saccharomyces Ferment Filtrate suits: normal, dry, combination, oily. Use with caution in: sensitive.

What is Saccharomyces Ferment Filtrate and what does it do in cosmetics?

Yeast fermentation product containing amino acids, vitamins, and minerals.

What's the INCI name for Saccharomyces Ferment Filtrate?

The INCI name is Saccharomyces Ferment Filtrate. It may also appear as: Saccharomyces Ferment Lysate Filtrate.

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