Evigrade

Succinic Acid

Mild dicarboxylic acid with anti-inflammatory and antibacterial action. Popular in Korean and Indian acne cosmetics.

Evidence by route

C

Topical application

In vitro studies show activity against Cutibacterium acnes and reduced inflammation cytokines. Large clinical trials remain insufficient.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Oily, Combination, Normal, Sensitive

About this ingredient

Succinic Acid (butanedioic acid) is a mild dicarboxylic acid. A natural Krebs cycle metabolite, present in amber and many plants. In dermatology – an anti-inflammatory and antibacterial active. Mechanism. Suppresses Cutibacterium acnes growth in vitro and reduces inflammation via NF-κB inhibition. Mild keratolytic and exfoliant – gentler than glycolic and salicylic acids. Where applied. Anti-acne products, especially popular in Korean and Indian cosmetics (The Inkey List Succinic Acid, Dr. Jart+ Peel-Off). Cosmetic concentration 2-10%, in spot treatments up to 15%. Evidence base. Klaus 2018 in vitro showed C. acnes suppression comparable to 2.5% benzoyl peroxide. Clinical RCTs are scarce: one small 30-patient 2021 study showed 30% acne reduction over 8 weeks at 10%. Evidence base is below salicylic acid and niacinamide. Safety. CIR confirmed safety at cosmetic concentrations. Non-sensitizing, gently tolerated, no stinging. Non-comedogenic. Pregnancy and lactation – safe. One of the few anti-acne ingredients allowed in gestation (alongside niacinamide, azelaic acid, sulfur).

Frequently asked questions

Is Succinic Acid safe during pregnancy?

Succinic Acid is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Succinic Acid for?

Succinic Acid suits: oily, combination, normal, sensitive.

What is Succinic Acid and what does it do in cosmetics?

Mild dicarboxylic acid with anti-inflammatory and antibacterial action.

What's the INCI name for Succinic Acid?

The INCI name is Succinic Acid. It may also appear as: Butanedioic Acid.

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