Minor
Amlodipine × Budesonide
Calcium channel blockers (dihydropyridines)×Inhaled corticosteroids (ICS)
Mechanism
No clinically significant direct interaction. With long-term oral budesonide, mild additive sodium retention may slightly reduce amlodipine's antihypertensive effect. Inhaled budesonide does not clinically affect BP.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
For short systemic budesonide courses, no adjustment needed. For long-term therapy, check BP monthly. If BP rises, increase amlodipine or add a diuretic.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.