Evigrade
MinorHerbal immunomodulators (local classification)×Anilides. Analgesics and antipyretics

Updated · Methodology

Mechanism

Echinacea purpurea modulates CYP1A2 and CYP3A4 in vitro, but the in vivo effect is minimal. No direct pharmacokinetic interaction with paracetamol has been described.

Symptoms

The combination usually causes no specific symptoms. Each drug's individual side effects remain.

Management

No dose adjustment needed. The combination is standard in over-the-counter use for acute respiratory infections. Echinacea's efficacy as an immunostimulant is not confirmed by large randomised trials (Cochrane Review 2014).

Check the full regimen, not just this pair

Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.

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Summary of a multi-drug list →

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Sources

Other interactions with Paracetamol