MinorSecond-generation antihistamines×Anilides. Analgesics and antipyretics
Updated · Methodology
Mechanism
Paracetamol and loratadine are metabolised by different pathways. No direct pharmacokinetic interaction.
Symptoms
The combination usually causes no specific symptoms. Each drug's individual side effects remain.
Management
No dose adjustment needed. The combination is standard in symptomatic formulations for acute respiratory infections and allergy.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Tylenol 8 HR Arthritis Pain (acetaminophen) – label (2020)– ; DailyMed setid 3af22fc8-e4e0-4863-8696-6bc1257047cb