CriticalAntifungal, triazole×Reversible P2Y12 receptor inhibitor
Updated · Methodology
Mechanism
Strong CYP3A4 inhibitor – ticagrelor rises 5-7 fold. FDA Section 4.3.
Symptoms
Bleeding.
Management
Combination contraindicated.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Brilinta (ticagrelor) prescribing information, Section 4.3 (2015)
- AEMPS: Ficha técnica: Itraconazol (nº registro 65775), sección 4.3 (2026)– AEMPS, CIMA, nº registro 65775, revisión 04/2026, sección 4.3