CriticalOxazolidinone antibiotic×Opioid analgesic, phenylpiperidine class
Updated · Methodology
Mechanism
Linezolid is a reversible MAO inhibitor. With meperidine – serotonin syndrome.
Symptoms
Hyperthermia, myoclonus.
Management
Combination contraindicated.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Demerol (meperidine) prescribing information (2017)– FDA Demerol label, boxed warning serotonergic
- AEMPS: Ficha técnica: Linezolid (nº registro 81569), sección 4.3 (2026)– AEMPS, CIMA, nº registro 81569, revisión 05/2026, sección 4.3