CriticalOxazolidinone antibiotic×Antidepressant, irreversible non-selective monoamine oxidase inhibitor (MAO-A and MAO-B), amphetamine derivative
Updated · Methodology
Mechanism
Cumulative MAO inhibition (irreversible tranylcypromine + reversible linezolid). Severe serotonin syndrome with tyramine load.
Symptoms
Hypertensive crisis, hyperthermia.
Management
Combination contraindicated.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- AEMPS: Ficha tecnica de Parnate (tranilcipromina) (2023)– AEMPS CIMA, ficha tecnica de Parnate, 2023