CriticalVinca alkaloid, microtubule assembly inhibitor×Triazole derivatives, systemic antifungals
Updated · Methodology
Mechanism
Strong CYP3A4 inhibitor. Fatal neurotoxicity.
Symptoms
Severe neuropathy.
Management
Combination contraindicated.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- FDA: Oncovin (vincristine) prescribing information (2013)– FDA Oncovin label, Section 4.3
- AEMPS: Ficha técnica: Voriconazol (nº registro 80105), sección 4.5 (2026)– AEMPS, CIMA, nº registro 80105, sección 4.5