Creatine
Natural compound synthesised by the body for muscle energy metabolism. Entered cosmetics from the anti-age segment: the manufacturer claims support for skin cell energy metabolism and an anti-age effect. Particularly common in German brands (Nivea Q10, anti-age line from Beiersdorf).
Evidence by route
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
The manufacturer has published a few studies with positive effects on skin density and wrinkle appearance, but independent replications are absent. Not compared head-to-head with retinoids or vitamin C. Clinically meaningful effect is not established, though tolerability is good.
- Lenz H et al. Skin Pharmacol Physiol. 2005;18(6):284-291.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
Frequently asked questions
Is Creatine safe during pregnancy?
Creatine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Creatine for?
Creatine suits: normal, dry, combination, sensitive.