Phytosphingosine
Sphingolipid and precursor of ceramides. Supports barrier function and regulates the skin microbiome through mild antimicrobial activity.
Barrier repair
Evidence by route
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Small clinical studies show effects on atopic and acne-prone skin through barrier support. Works in microdoses of 0.05–0.2% in formulas.
Tolerability and safety
Irritation potential
LowAllergen risk
LowPregnancy
SafeSkin types
Suitable for
OilyDrySensitiveCombinationNormal
Frequently asked questions
Is Phytosphingosine safe during pregnancy?
Phytosphingosine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Phytosphingosine for?
Phytosphingosine suits: oily, dry, sensitive, combination, normal.