EEvigrade
RU

Allantoin

Naturally derived uric acid derivative. Accelerates cell proliferation, reduces irritation, and softens the stratum corneum.

SoothingBarrier repair

Evidence by route

Topical application

C

Weak evidence. In vitro data, open-label studies, or expert consensus.

Recognized as GRAS (Generally Recognized As Safe) by FDA. Clinical studies in atopic dermatitis and wound healing demonstrate moderate healing and softening effects. Well tolerated; allergic reactions are extremely rare. Independent large RCTs are limited.

  • Araújo LU et al. Rev Bras Farmacogn. 2010;20(1):156-168.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

OilyCombinationSensitiveNormalDry

Frequently asked questions

Is Allantoin safe during pregnancy?

Allantoin is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Allantoin for?

Allantoin suits: oily, combination, sensitive, normal, dry.