Evigrade

Arabinogalactan

Branched polysaccharide from larch with prebiotic action. Feeds beneficial skin microbiota, forms a soft protective film and reinforces the barrier.

Evidence by route

C

Topical application

Safe prebiotic polysaccharide. Topical microbiome effects rely on lab models, clinical data remain limited.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Oily, Combination, Sensitive

About this ingredient

Arabinogalactan is a branched polysaccharide from larch (Larix laricina, Larix occidentalis). Contains arabinose and galactose in a 1:6 ratio. Produced by water extraction from wood. Mechanism. Prebiotic – selectively feeds beneficial skin microbiota (S. epidermidis, bifidobacteria). Forms a soft protective film on the skin that holds moisture. Immunomodulator: stimulates interferon synthesis and NK-cell activity. In vitro antioxidant activity. Where applied. Serums and creams with prebiotic positioning (0.5–5%), moisturizers, atopic-skin creams, post-procedure products. In Spain – Sesderma Acglicolic, Mesoestetic. Evidence base. Few direct clinical RCTs with skin endpoints. Oral arabinogalactan in inflammatory bowel disease has moderate evidence (Kelly 1999). On skin – in vitro microbiome effect, weak clinical data. Safety. CIR confirmed safety at cosmetic concentrations. Hypoallergenic, non-irritating, non-comedogenic. Pregnancy and lactation – safe. Acceptable at any stage. Functional role. A prebiotic polysaccharide with a plausible mechanism and moderate evidence. An add-on to a moisturizing and barrier-supporting base.

Frequently asked questions

Is Arabinogalactan safe during pregnancy?

Arabinogalactan is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Arabinogalactan for?

Arabinogalactan suits: normal, dry, oily, combination, sensitive.

What is Arabinogalactan and what does it do in cosmetics?

Branched polysaccharide from larch with prebiotic action.

What's the INCI name for Arabinogalactan?

The INCI name is Arabinogalactan.

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