Branched polysaccharide from larch with prebiotic action. Feeds beneficial skin microbiota, forms a soft protective film and reinforces the barrier.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Safe prebiotic polysaccharide. Topical microbiome effects rely on lab models, clinical data remain limited.
Arabinogalactan is a branched polysaccharide from larch (Larix laricina, Larix occidentalis). Contains arabinose and galactose in a 1:6 ratio. Produced by water extraction from wood. Mechanism. Prebiotic – selectively feeds beneficial skin microbiota (S. epidermidis, bifidobacteria). Forms a soft protective film on the skin that holds moisture. Immunomodulator: stimulates interferon synthesis and NK-cell activity. In vitro antioxidant activity. Where applied. Serums and creams with prebiotic positioning (0.5–5%), moisturizers, atopic-skin creams, post-procedure products. In Spain – Sesderma Acglicolic, Mesoestetic. Evidence base. Few direct clinical RCTs with skin endpoints. Oral arabinogalactan in inflammatory bowel disease has moderate evidence (Kelly 1999). On skin – in vitro microbiome effect, weak clinical data. Safety. CIR confirmed safety at cosmetic concentrations. Hypoallergenic, non-irritating, non-comedogenic. Pregnancy and lactation – safe. Acceptable at any stage. Functional role. A prebiotic polysaccharide with a plausible mechanism and moderate evidence. An add-on to a moisturizing and barrier-supporting base.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Arabinogalactan is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Arabinogalactan suits: normal, dry, oily, combination, sensitive.
Branched polysaccharide from larch with prebiotic action.
The INCI name is Arabinogalactan. It may also appear as: Арабиногалактан.
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