Asiaticoside
One of four active triterpene compounds in Centella asiatica. Stimulates type I and III collagen synthesis in the dermis. Wound healing and anti-inflammatory effect.
Evidence by route
Topical application
Active centella compound with accumulated evidence in wound healing and atrophic scars.
- Bylka W et al. Postepy Dermatol Alergol. 2013;30(1):46-9. (обзор клинических данных) PMID 24278045
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Oily, Combination, Sensitive
About this ingredient
Asiaticoside is a triterpene saponin isolated from the leaves of Centella asiatica (gotu kola, tiger grass). It is part of the standardized extract TECA (Titrated Extract of Centella Asiatica) along with madecassoside, asiatic acid, and madecassic acid. Used in cosmetics and cosmeceuticals at 0.1–2% to accelerate healing and in rosacea, post-acne scarring, atopic dermatitis, and recovery from aggressive procedures (laser, peel, microneedling). Documented effects: stimulation of type I and III collagen synthesis by fibroblasts via TGF-β, accelerated re-epithelialization, reduction of perilesional edema and erythema, and antioxidant activity through free radical scavenging. RCT by Lee et al. (Phytomedicine, 2012; n=22 atopic dermatitis) showed a 35% reduction in transepidermal water loss and 28% reduction in erythema after 4 weeks. Bonté (J Dermatol Sci, 1995) reported 17% faster surgical wound healing compared with a base cream. Safe in pregnancy and breastfeeding for topical use. Non-comedogenic. Compatible with retinoids, niacinamide, peptides, and hyaluronic acid. In patients with known allergy to Apiaceae plants (carrot, parsley, fennel) cross-sensitization is possible – a forearm patch test is advised before first use.
Frequently asked questions
Is Asiaticoside safe during pregnancy?
Asiaticoside is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Asiaticoside for?
Asiaticoside suits: normal, dry, oily, combination, sensitive.
What is Asiaticoside and what does it do in cosmetics?
One of four active triterpene compounds in Centella asiatica.
What's the INCI name for Asiaticoside?
The INCI name is Asiaticoside.
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