An emulsifier for water-in-oil formulas. It blends the phases and stabilizes the cream. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A functional emulsifier. Safe.
Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate is an emulsifier for water-in-oil formulas, listed in INCI under the same name. It joins the water and oil phases and stabilizes the cream so it does not separate over time. It shows up in rich creams, balms and sunscreens. This is a functional formulation component, not a skincare active. It sets the product's structure and shelf stability, but it does not treat the skin itself. It does its technical job reliably. Applied topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy potential. It is a polyglycerol emulsifier, generally well tolerated and unlikely to cause reactions.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate suits: normal, dry, combination, oily, sensitive.
An emulsifier for water-in-oil formulas.
The INCI name is Polyglyceryl-4 Diisostearate/Polyhydroxystearate/Sebacate. It may also appear as: Полиглицерил-4 диизостеарат/полигидроксистеарат/себацат.
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