Sphingomonas Ferment Extract
Postbiotic – fermentation product of Sphingomonas bacteria. Part of the 'microbiome-friendly' cosmetics trend. Evidence base is developing.
Evidence by route
Topical application
Postbiotic with accumulated in vitro and pilot clinical data.
How to read tiers A–F
- DNo data, or very weak or conflicting data
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Oily, Combination, Sensitive
About this ingredient
Sphingomonas Ferment Extract is a postbiotic – a fermentation product of Sphingomonas bacteria that live in hot springs. Part of the microbiome-friendly cosmetics trend. Mechanism. Contains low-molecular peptides, exopolysaccharides and fermentation metabolites. Marketing claims skin-microbiome support and anti-inflammatory effects. The exact mechanism on human skin is not yet detailed at molecular level. Where applied. K-beauty and J-beauty serums and creams, with limited use in European brands. Concentration usually below 1%. Evidence base. In vitro – suppression of inflammatory cytokines (IL-6, IL-8) in keratinocyte culture. Clinical studies in patients with specific indications are not yet available. Safety. CIR has not issued a dedicated report. Manufacturers (ID Bio, Cosphatec) have acute-toxicity and sensitisation tests – safety profile is favourable. Pregnancy and lactation – safe at cosmetic concentrations.
Frequently asked questions
Is Sphingomonas Ferment Extract safe during pregnancy?
Sphingomonas Ferment Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Sphingomonas Ferment Extract for?
Sphingomonas Ferment Extract suits: normal, dry, oily, combination, sensitive.
What is Sphingomonas Ferment Extract and what does it do in cosmetics?
Postbiotic – fermentation product of Sphingomonas bacteria.
What's the INCI name for Sphingomonas Ferment Extract?
The INCI name is Sphingomonas Ferment Extract.
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