Postbiotic – fermentation product of Sphingomonas bacteria. Part of the 'microbiome-friendly' cosmetics trend. Evidence base is developing.
Topical application
DVery weak or conflicting data.
Postbiotic with accumulated in vitro and pilot clinical data.
Sphingomonas Ferment Extract is a postbiotic – a fermentation product of Sphingomonas bacteria that live in hot springs. Part of the microbiome-friendly cosmetics trend. Mechanism. Contains low-molecular peptides, exopolysaccharides and fermentation metabolites. Marketing claims skin-microbiome support and anti-inflammatory effects. The exact mechanism on human skin is not yet detailed at molecular level. Where applied. K-beauty and J-beauty serums and creams, with limited use in European brands. Concentration usually below 1%. Evidence base. In vitro – suppression of inflammatory cytokines (IL-6, IL-8) in keratinocyte culture. Clinical studies in patients with specific indications are not yet available. Safety. CIR has not issued a dedicated report. Manufacturers (ID Bio, Cosphatec) have acute-toxicity and sensitisation tests – safety profile is favourable. Pregnancy and lactation – safe at cosmetic concentrations.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Sphingomonas Ferment Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Sphingomonas Ferment Extract suits: normal, dry, oily, combination, sensitive.
Postbiotic – fermentation product of Sphingomonas bacteria.
The INCI name is Sphingomonas Ferment Extract.
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