A preservative and antiseptic (PHMB). Effective at low concentrations, common in micellar water and sensitive-skin products. The EU caps its concentration (Regulation 1223/2009); within that limit it is well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
An effective preservative; EU caps its concentration. Within the limit it is well tolerated, with rare contact allergy documented.
Irritation potential
LowAllergen risk
ModeratePregnancy
SafeSuitable for
Use with caution
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Polyaminopropyl Biguanide is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Polyaminopropyl Biguanide suits: normal, dry, combination, oily, sensitive. Use with caution in: sensitive.
A preservative and antiseptic (PHMB).
The INCI name is Polyaminopropyl Biguanide. It may also appear as: PHMB, Полиаминопропил бигуанид, Polyhexamethylene Biguanide.
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