Salicylic Acid

Beta-hydroxy acid (BHA) with lipophilic properties: penetrates sebaceous glands, dissolves plugs, and exerts anti-inflammatory effects.

AcneBrightening

Evidence by route

Topical application

Proven efficacy. Two or more independent RCTs with instrumental endpoints.

RCTs and meta-analyses confirm efficacy for comedonal and inflammatory acne. FDA-approved as an OTC acne drug at 0.5–2% concentrations. Also used for ichthyosis, psoriasis, seborrheic dermatitis.

Arif T. Clin Cosmet Investig Dermatol. 2015;8:455-461.
Decker A et al. Semin Cutan Med Surg. 2008;27(3):170-176.

Working concentrations

0.5–2% in OTC products

Tolerability and safety

Irritation potential

Medium

Allergen risk

Low

Pregnancy

Caution

Skin types

Suitable for

OilyCombination

Use with caution

SensitiveDry

Combinations with other ingredients

Works well with

NiacinamideНиацинамид

Salicylic acid works on comedones, niacinamide on inflammation and barrier. Pair performs well in acne.

Does not combine with

RetinolРетинол

Simultaneous use raises irritation potential. Alternate every other day or split morning/evening.

Glycolic AcidГликолевая кислота

Two acid exfoliants at once are excessive. Alternate: AHA one evening, BHA another, to avoid barrier overload.

Frequently asked questions

Is Salicylic Acid safe during pregnancy?

Salicylic Acid should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Salicylic Acid for?

Salicylic Acid suits: oily, combination. Use with caution in: sensitive, dry.

Can Salicylic Acid irritate the skin?

Salicylic Acid has moderate irritation potential. Sensitive skin may show a transient reaction that usually settles with adaptation.