CriticalmTOR kinase inhibitor – immunosuppressant and antineoplastic×Second-generation systemic triazole antifungal
Updated · Methodology
Mechanism
Strong CYP3A4 inhibitor. Everolimus rises 9-fold.
Symptoms
Immunosuppression, nephrotoxicity.
Management
Combination contraindicated.
Check the full regimen, not just this pair
Opens the checker with these two drugs prefilled. Add the rest of the regimen and recompute additive risks.
Summary of a multi-drug list →
Medicine list: everything you take in one place →
Sources
- EMA: Votubia (everolimus) EPAR – EMA (2024)– EMA EPAR Certican
- AEMPS: Ficha técnica: Everolimus (nº registro 84203), sección 4.5 (2024)– AEMPS, CIMA, nº registro 84203, sección 4.5