Evigrade

Acetyl Dipeptide-1 Cetyl Ester

A lipophilic peptide (trade name Calmosensine). Promoted as a soothing ingredient for sensitive skin. Data rests on small manufacturer studies, with little independent trial support. Safe, but a marked effect should not be expected.

Evidence by route

C

Topical application

A soothing peptide with thin evidence: mostly manufacturer data, little independent testing. Safe, with a modest effect.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

Frequently asked questions

Is Acetyl Dipeptide-1 Cetyl Ester safe during pregnancy?

Acetyl Dipeptide-1 Cetyl Ester is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Acetyl Dipeptide-1 Cetyl Ester for?

Acetyl Dipeptide-1 Cetyl Ester suits: normal, dry, combination, oily, sensitive.

What is Acetyl Dipeptide-1 Cetyl Ester and what does it do in cosmetics?

A lipophilic peptide (trade name Calmosensine).

What's the INCI name for Acetyl Dipeptide-1 Cetyl Ester?

The INCI name is Acetyl Dipeptide-1 Cetyl Ester. It may also appear as: Calmosensine.

See Acetyl Dipeptide-1 Cetyl Ester in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

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