Evigrade
DrugsCosmetic ingredientsCalculatorsInteractionsEvigrade SkinEvigrade Meds ↗
ConditionsJournalMethodologyPro for practitioners
ESRU

Aloe Barbadensis Leaf Polysaccharides

Purified aloe vera polysaccharide fraction – acemannan and related glucomannans. Deep hydration and anti-inflammatory action. Pregnancy-safe.

Evidence by route

B

Topical application

Polysaccharides with confirmed hydration and wound healing. Moderate evidence.

  • Maenthaisong R et al. Aloe vera for burn wounds: systematic review. Burns 2007;33:713-718. PMID 17499928
  • Hekmatpou D et al. Acemannan in wound healing: systematic review. Iran J Med Sci 2019. PMID 30666070
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Aloe leaf polysaccharides are a purified glucomannan fraction from the flesh of Aloe barbadensis. INCI: Aloe Barbadensis Leaf Polysaccharides. The main active component is acemannan, an acetylated polysaccharide with a mass of 50-1500 kDa. In cosmetics they work as a strong humectant with intrinsic activity. The polysaccharides form a hydrogel on the skin surface, retaining 8-10 times their weight in water. Acemannan also has anti-inflammatory and immunomodulatory action – it stimulates macrophages and accelerates healing of superficial wounds and sunburns. Used in hydrating gels, after-sun products, sensitive-skin creams and post-procedure formulas. Use levels run from 0.1 to 5% (the purified fraction is significantly more concentrated than aloe leaf juice). Pregnancy safety. Skin absorption into the systemic circulation is minimal. Topically safe. Oral aloe during pregnancy is not recommended because of anthraquinones, but the polysaccharide fraction does not contain them. Skin profile. Very low irritation and allergen potential. Non-comedogenic. Suitable for all skin types, especially sensitive, dehydrated and irritated. Moderate evidence (B) – clinical data for burn healing and hydration improvement.

Frequently asked questions

Is Aloe Barbadensis Leaf Polysaccharides safe during pregnancy?

Aloe Barbadensis Leaf Polysaccharides is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Aloe Barbadensis Leaf Polysaccharides for?

Aloe Barbadensis Leaf Polysaccharides suits: normal, dry, combination, oily, sensitive.

What is Aloe Barbadensis Leaf Polysaccharides and what does it do in cosmetics?

Purified aloe vera polysaccharide fraction – acemannan and related glucomannans.

Is Aloe Barbadensis Leaf Polysaccharides comedogenic?

On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.

What's the INCI name for Aloe Barbadensis Leaf Polysaccharides?

The INCI name is Aloe Barbadensis Leaf Polysaccharides. It may also appear as: Aloe Vera Polysaccharides, Acemannan.

See Aloe Barbadensis Leaf Polysaccharides in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar in action

Published: · updated: