Calendula Extract
Calendula flower extract with anti-inflammatory, wound-healing, and antimicrobial properties. Contains triterpenes, flavonoids, and carotenoids.
Evidence by route
Topical application
Small clinical studies show accelerated epithelialization and anti-inflammatory effects in dermatitis and minor wounds. Cross-reaction possible in people allergic to Asteraceae (Compositae). No large RCTs.
- Leach MJ. Wounds. 2008;20(8):236-243. PMID 25941793
How to read tiers A–F
- CWeak evidence. In vitro data, open-label studies, or expert consensus
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Sensitive, Dry, Normal
About this ingredient
Calendula Extract (Calendula Officinalis Flower Extract) is a water, glycolic, or oil extract of marigold flowers. Contains triterpene saponins (calendulosides), flavonoids (quercetin, isorhamnetin), carotenoids (lutein, β-carotene), essential oils. Mechanism. Anti-inflammatory action via NF-κB suppression and reduced IL-6, IL-1β, TNF-α in skin. Speeds up fibroblast and keratinocyte migration in wounds – suitable for post-procedure recovery. Antimicrobial action against Staphylococcus aureus and Candida albicans is described in vitro. Carotenoids and flavonoids provide a mild antioxidant effect. Where applied. Baby cosmetics (Mustela Calendula, Weleda Baby), creams for sensitive and reactive skin, post-procedure products, hand and body balms, nappy-rash and sunburn products. Concentration 0.5–5%. In Spain – Weleda Calendula, Bübchen Pflegesalbe, Bioderma ABCDerm. Evidence base. Pommier 2004 (n=254, randomised) showed significant reduction of radiation dermatitis in breast-cancer patients on radiotherapy with calendula creams. Khairnar 2013 described faster wound healing after surgery. For paediatric atopic dermatitis Foster 2010 included calendula on the safe-emollient list. Safety. CIR confirmed cosmetic safety. Cross-allergy with Asteraceae (mugwort, ragweed, chamomile) in 5–10% of pollinosis patients – isolated contact dermatitis reports. Hypoallergenic in the general population, non-comedogenic. Pregnancy and lactation – safe topically. Used without restriction. One of the main emollients for gestational skin and breast care during breastfeeding (nipple-fissure healing). Particularly suitable for. Sensitive and reactive skin, atopic dermatitis, infant nappy rash, post-procedure recovery, after radiotherapy (with radiologist agreement), mild inflammatory skin changes. Not for patients with Asteraceae allergy.
Frequently asked questions
Is Calendula Extract safe during pregnancy?
Calendula Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Calendula Extract for?
Calendula Extract suits: sensitive, dry, normal.
What is Calendula Extract and what does it do in cosmetics?
Calendula flower extract with anti-inflammatory, wound-healing, and antimicrobial properties.
What's the INCI name for Calendula Extract?
The INCI name is Calendula Officinalis Flower Extract.
See Calendula Extract in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
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