Ceramides

INCI: Ceramide NP / Ceramide AP / Ceramide EOP

Lipids constituting approximately 50% of the stratum corneum. Ceramide deficiency is a key factor in the pathogenesis of atopic dermatitis and xerosis.

Barrier repairMoisturizing

Evidence by route

Topical application

Limited evidence. One RCT or several controlled studies with limitations.

RCTs in atopic dermatitis show reduction in transepidermal water loss (TEWL), decreased SCORAD index, and reduced flare frequency. Comparative studies against plain emollients favor ceramide-containing formulations.

Hon KL et al. J Dermatolog Treat. 2013;24(3):182-186.
Meckfessel MH et al. J Am Acad Dermatol. 2014;71(1):177-184.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

DrySensitiveNormalCombination

Combinations with other ingredients

Works well with

RetinolРетинол

Ceramides restore the barrier that retinol weakens during adaptation. A must-pair for sensitive skin.

Hyaluronic AcidГиалуроновая кислота

Hyaluronic acid pulls water, ceramides hold it in the barrier. A baseline moisturizing combination.

Frequently asked questions

Is Ceramides safe during pregnancy?

Ceramides is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Ceramides for?

Ceramides suits: dry, sensitive, normal, combination.