Evigrade

Cyperus Rotundus Root Extract

Contains ciroufene; studied as a tyrosinase inhibitor (brightening).

Evidence by route

C

Topical application

Plant extract. Clinically meaningful effect on human skin is not supported by robust evidence; data limited to in vitro / lab models.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Unknown

About this ingredient

Cyperus Rotundus Root Extract is derived from the rhizome of Cyperus rotundus, a tropical herbaceous sedge widespread in Africa, Asia, the Mediterranean. Known in Ayurveda as Mustaka, in traditional Chinese medicine as Xiang Fu. Composition. Essential oil with ciroufene, α-cyperone, β-sesquiphellandrene. Phenolic compounds, flavonoids, triterpenes. Mechanism. In vitro the extract inhibits tyrosinase and suppresses melanogenesis. It also shows anti-inflammatory activity via 5-lipoxygenase suppression. Manufacturers market it as a brightening and anti-inflammatory ingredient. Where applied. Anti-hyperpigmentation serums and creams, tone-evening products, anti-aging products with brightening positioning. In Spain – niche Ayurvedic brands, in formulas with a 'brightening from nature' marketing angle. Evidence base. Topical clinical data are limited. Akram 2020 review confirmed brightening activity in vitro and in animal models. No direct human RCTs in hyperpigmentation patients; efficacy remains declarative. Safety. CIR has not issued a direct evaluation. By the plant extract profile – low irritation and allergy risk. Rare reactions possible in patients allergic to the sedge family. Pregnancy and lactation – with caution. In traditional medicine Cyperus rotundus was used for menstrual cycle regulation; it isn't prescribed orally during pregnancy. Topical cosmetic concentrations are likely safe, but no direct data. Best suited to: hyperpigmentation, melasma, post-acne spots within a multi-component program. Not a primary brightening active – proven molecules (azelaic acid, niacinamide, cysteamine, tretinoin) work more reliably.

Frequently asked questions

Is Cyperus Rotundus Root Extract safe during pregnancy?

Safety data for Cyperus Rotundus Root Extract during pregnancy is insufficient. Best avoided when in doubt.

What is Cyperus Rotundus Root Extract and what does it do in cosmetics?

Contains ciroufene; studied as a tyrosinase inhibitor (brightening).

What's the INCI name for Cyperus Rotundus Root Extract?

The INCI name is Cyperus Rotundus Root Extract.

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