Contains phytosterols and tocopherols. Trace gossypol requires careful processing.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Plant extract. Clinically meaningful effect on human skin is not supported by robust evidence; data limited to in vitro / lab models.
Cotton seed extract (Gossypium Herbaceum Cotton Seed Extract) is obtained from cotton seeds. Contains phytosterols, tocopherols, phospholipids, flavonoids. Where applied. Soothing and repair creams, sensitive skin products. Found in Asian and natural cosmetics. Gossypol controversy. Raw cotton oil contains gossypol – a polyphenol toxic to the liver and male reproductive system. Purified seed extract for cosmetics must have gossypol removed. The manufacturer must document raw material purity. Evidence base. Direct clinical RCTs are few; Asian studies (Choi 2015) showed in vitro anti-inflammatory effect. Marketing claims exceed the evidence base. Safety. CIR has not made a separate assessment. Cross-reactivity possible in patients allergic to cotton (rare). Pregnancy and lactation – no data (UNKNOWN). Gossypol is contraindicated in pregnancy; with purified extract the risk is minimal, but avoid as a precaution.
Irritation potential
LowAllergen risk
LowPregnancy
UnknownThe Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Safety data for Gossypium Herbaceum (Cotton) Seed Extract during pregnancy is insufficient. Best avoided when in doubt.
Contains phytosterols and tocopherols.
The INCI name is Gossypium Herbaceum (Cotton) Seed Extract. It may also appear as: Экстракт семян хлопка.
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