A menthol derivative with a mild cooling effect. It gives freshness without a sharp menthol smell. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A cooling functional ingredient. Safe.
Menthyl PCA (INCI Menthyl PCA) is a derivative of menthol joined to pyrrolidone carboxylic acid. In a formula it gives a gentle cooling sensation and a light freshness, but without the sharp menthol smell or a strong cold hit, which is why it is liked in deodorants, toners and facial products. On efficacy, this is a sensory ingredient, not a skincare active. The freshness it creates is a sensory effect through cold receptors. The PCA part is theoretically linked to hydration, but in the role of a menthol derivative its job is the pleasant sensation, not skin care. During pregnancy and breastfeeding it can be used. Applied topically in a product the ingredient is systemically negligible, with no restrictions. Tolerance is good, and that is its advantage over pure menthol. The irritation potential is low, the allergy risk is low, and the ingredient suits sensitive skin. The gentle cooling effect without harshness makes it a handy substitute for menthol for people who find menthol too aggressive.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Menthyl PCA is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Menthyl PCA suits: normal, dry, combination, oily, sensitive.
A menthol derivative with a mild cooling effect.
The INCI name is Menthyl PCA. It may also appear as: Ментил ПКА.
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