Evigrade

Mexoryl XL

Patented lipophilic broad-spectrum filter by L'Oreal. Covers both UVB and UVA ranges and stays stable under sunlight.

INCI: Drometrizole Trisiloxane

Evidence by route

B

Topical application

Oil-soluble counterpart of Mexoryl SX with broad coverage. Combines well with other filters and boosts the final protection factor.

How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Caution
Suitable for
Normal, Dry, Oily, Combination, Sensitive

About this ingredient

Mexoryl XL (Drometrizole Trisiloxane) is a photostable broad-spectrum UV filter produced by L'Oréal. Absorbs UVA (320–400 nm) and part of UVB (290–320 nm). Mechanism. The chromophore absorbs UV energy and converts it to heat. Unlike avobenzone, it is photostable – does not break down under UV light. The siloxane chain provides water resistance and application aesthetics. Where applied. Only in L'Oréal Group products (La Roche-Posay Anthelios, Vichy Capital Soleil, Garnier Ambre Solaire). EU Regulation 1223/2009 concentration – up to 15%. Widely available in Spain in La Roche-Posay and Vichy lines. Not permitted in the US: it is not in the FDA over-the-counter sunscreen monograph (M020), and Anthelios SX, approved in 2006, contains a different L'Oréal filter, ecamsule (Mexoryl SX). Evidence base. The Moyal 2008 clinical study showed protection against photoimmunosuppression and UVA-induced pigmentation. SCCS Opinion SCCS/1185/08 confirmed safety at concentrations up to 15%. Often combined with Mexoryl SX (Ecamsule) and avobenzone for broad-spectrum protection. Safety. Well tolerated. Contact allergies are rare (<0.5%). Systemic skin absorption is minimal. Pregnancy and lactation – manufacturers advise caution. No direct data. First-line alternative in pregnancy – mineral filters (titanium dioxide, zinc oxide). If a chemical filter is chosen – Mexoryl XL is preferred due to large molecule and minimal systemic absorption.

Frequently asked questions

Is Mexoryl XL safe during pregnancy?

Mexoryl XL should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.

What skin types is Mexoryl XL for?

Mexoryl XL suits: normal, dry, oily, combination, sensitive.

What is Mexoryl XL and what does it do in cosmetics?

Patented lipophilic broad-spectrum filter by L'Oreal.

What's the INCI name for Mexoryl XL?

The INCI name is Drometrizole Trisiloxane.

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