Lipopeptide with palmitic acid for better penetration. Claimed soothing effect.
Topical application
DVery weak or conflicting data.
Marketing peptide without independent clinical data.
Palmitoyl Dipeptide-7 is a synthetic lipopeptide: the L-alanyl-L-threonine dipeptide with an attached palmitic acid. The palmitoyl moiety enables penetration through the lipophilic skin barrier. Mechanism. Claimed action – blockade of the α-MSH receptor in melanocytes – reduces melanin production and lightens hyperpigmentation. Based on manufacturer studies. Where applied. Brightening serums and creams. Formula concentration 0.01–0.1% (as part of peptide complexes). Evidence base. Independent clinical RCTs are few. The evidence base is inferior to niacinamide, N-acetyl glucosamine, MAP. CIR has not published a separate assessment. Safety. Hypoallergenic at cosmetic concentrations, non-comedogenic. Pregnancy and lactation – manufacturers advise caution. No direct pregnancy data – synthetic palmitoyl peptides have not been studied in detail.
Irritation potential
LowAllergen risk
LowPregnancy
CautionSuitable for
The Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Palmitoyl Dipeptide-7 should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
Palmitoyl Dipeptide-7 suits: normal, dry, oily, combination, sensitive.
Lipopeptide with palmitic acid for better penetration.
The INCI name is Palmitoyl Dipeptide-7.
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