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Raphanus Sativus (Radish) Seed Extract

Fermented radish seed extract sometimes used as a preservative alternative.

Evidence by route

C

Topical application

Plant extract. Clinically meaningful effect on human skin is not supported by robust evidence; data limited to in vitro / lab models.

How to read tiers A–F
  • CWeak evidence. In vitro data, open-label studies, or expert consensus

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Unknown

About this ingredient

Radish seed extract (Raphanus Sativus Seed Extract) is a fermentation product of Leuconostoc kimchii lactobacteria grown on radish seeds. It contains peptides and antimicrobial metabolites that suppress yeast, mold, and gram-positive bacteria. The marketing name is Leucidal Liquid. Where applied. In niche and clean-beauty formulas as a 'natural alternative' to phenoxyethanol, parabens, and benzoate. Concentration 2-4%, usually paired with a second preservative (e.g., glyceryl caprylate or anisic acid). Pure Leucidal does not provide broad-spectrum protection. Evidence base. Challenge tests (USP 51, ISO 11930) show good activity against gram-positive bacteria, but limited activity against gram-negative organisms (Pseudomonas) and molds. Works better in acidic environments (pH < 5.5). Formulas with pH > 6 need additional preservatives. Safety. Approved in the EU as a cosmetic ingredient. Allergic potential is low, but rare irritation has been described in people with severely impaired barrier. Non-comedogenic. 'Natural preservative' controversy. 'Natural' does not mean safer – the preservative load is weaker, and without backup the formula carries a higher risk of microbial contamination. ECOcert and Cosmos accept radish ferments but require challenge-test evidence of efficacy. Pregnancy and lactation – likely safe. No systemic absorption, extensive use experience. No restrictions.

Frequently asked questions

Is Raphanus Sativus (Radish) Seed Extract safe during pregnancy?

Safety data for Raphanus Sativus (Radish) Seed Extract during pregnancy is insufficient. Best avoided when in doubt.

What is Raphanus Sativus (Radish) Seed Extract and what does it do in cosmetics?

Fermented radish seed extract sometimes used as a preservative alternative.

What's the INCI name for Raphanus Sativus (Radish) Seed Extract?

The INCI name is Raphanus Sativus (Radish) Seed Extract.

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