Schisandra contains lignans (schizandrin); studied as an adaptogen.
Topical application
CWeak evidence. In vitro data, open-label studies, or expert consensus.
Plant extract. Clinically meaningful effect on human skin is not supported by robust evidence; data limited to in vitro / lab models.
Schisandra chinensis extract is an extract from berries of wild schisandra, a vine from northern China, the Russian Far East, Korea. Active compounds: lignans (schisandrin, schisandrol, gomisin), triterpenes, flavonoids, organic acids. In traditional East Asian medicine schisandra is classified as an adaptogen – a substance to increase stress resilience. Where applied. Anti-aging serums and creams with 'adaptogen for skin' marketing (0.1-2%), products against photoaging, anti-pollution formulas, products for tired stressed skin. On the Spanish market – in niche natural and K-beauty lines. Evidence base. Systemic (oral) schisandra studies covered stress adaptation, physical exertion, mild cognitive impairment. Cochrane 2010 adaptogen review showed weak and inconsistent evidence quality. Topical clinical RCTs in humans with schisandra extract are isolated; antioxidant potential is proven in vitro. Marketing vs reality. The 'pollution defense' and 'adaptogen for skin' marketing in commercial formulas rests on in vitro data and the general reputation of systemic use. Real clinical skin effects are poorly studied. Safety. EU CosIng permits use. Systemically with oral intake schisandra causes heartburn, insomnia, tachycardia in some patients – topically no such effects, systemic absorption is minimal. Allergic reactions are rare. Pregnancy and lactation – use with caution. Systemically schisandra is contraindicated in pregnancy (uterine stimulation, psychotropic activity). Topically on intact skin systemic absorption is essentially absent, but due to lack of data manufacturers recommend avoiding. Alternatives: niacinamide, peptides, vitamin E.
Irritation potential
LowAllergen risk
LowPregnancy
UnknownThe Evigrade extension adds an evidence panel to Wildberries, Goldapple, Letu, iHerb, Sephora and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Safety data for Schisandra Chinensis Extract during pregnancy is insufficient. Best avoided when in doubt.
Schisandra contains lignans (schizandrin); studied as an adaptogen.
The INCI name is Schisandra Chinensis Extract. It may also appear as: Экстракт лимонника китайского.
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