Sodium PCA

Sodium salt of pyrrolidone carboxylic acid – the primary component of the natural moisturizing factor (NMF). Attracts and retains moisture in the stratum corneum.

Moisturizing

Evidence by route

Topical application

Weak evidence. In vitro data, open-label studies, or expert consensus.

Moisturizing effect confirmed by clinical data in xerosis. As an NMF component, it is highly skin-compatible. No standalone large RCTs – typically used in combination with other humectants.

Rawlings AV et al. Int J Cosmet Sci. 2004;26(4):217-233.

Tolerability and safety

Irritation potential

Low

Allergen risk

Low

Pregnancy

Safe

Skin types

Suitable for

OilyDrySensitiveCombinationNormal

Frequently asked questions

Is Sodium PCA safe during pregnancy?

Sodium PCA is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Sodium PCA for?

Sodium PCA suits: oily, dry, sensitive, combination, normal.