Evigrade

Soluble Proteoglycan

A biopolymer from connective tissue. It draws water, helps hold it in skin and gives firmness. Well tolerated.

Evidence by route

B

Topical application

A moisturizing biopolymer. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Soluble Proteoglycan is a biopolymer from connective tissue, a protein bound to glycosaminoglycan chains. Its INCI matches the name. In a formula it acts as a humectant: it draws water into the surface layer and helps hold it, which gives a sense of greater firmness and comfort. As a surface hydrator it does its job and the feel is usually pleasant. Be realistic about the anti-aging claim: it hydrates well and improves skin short-term, but it does not rebuild the dermal matrix from the outside. It is a good supporting hydration component, not a stand-in for your own collagen. Topically it has no systemic relevance, so it can be used during pregnancy and breastfeeding. Tolerance is good, with low irritation and allergy, fine for sensitive skin. There is no evidence of meaningful comedogenicity.

Frequently asked questions

Is Soluble Proteoglycan safe during pregnancy?

Soluble Proteoglycan is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Soluble Proteoglycan for?

Soluble Proteoglycan suits: normal, dry, combination, oily, sensitive.

What is Soluble Proteoglycan and what does it do in cosmetics?

A biopolymer from connective tissue.

What's the INCI name for Soluble Proteoglycan?

The INCI name is Soluble Proteoglycan.

See Soluble Proteoglycan in a product composition right on the store page

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Similar role in the formula

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Moisturizing, Anti-aging

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