Strontium Chloride
Strontium salt that selectively suppresses sensory C-fiber activity in skin. Calms itching and stinging, features in soothing products after acids and retinoids.
Evidence by route
Topical application
Short-term anti-irritant effect is confirmed by small RCTs. Long-term safety with daily use is poorly studied.
How to read tiers A–F
- CWeak evidence. In vitro data, open-label studies, or expert consensus
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Caution
- Suitable for
- Sensitive, Normal
About this ingredient
Strontium Chloride (SrCl2) is an inorganic strontium salt. In dermatology it is used as a selective suppressor of skin sensory C-fibre activity responsible for itch and burning. Mechanism. Strontium blocks calcium-dependent ion channels in peripheral skin nociceptors, lowering the itch and sting signal. Effect is fast – within 10-20 minutes of application. Acts locally, no significant systemic absorption. Where applied. Anti-sting products after acids, retinoids, peels; itchy-dermatosis creams; post-wax-epilation and post-laser products. Concentration 4-10%. Evidence base. Hahn 1999, 2001 in itch and sting patients showed fast relief (within 5-15 minutes) at 4% strontium chloride. Cosmetic use in premium post-procedure care. Safety. CIR confirmed safety at cosmetic concentrations. Not to be confused with radioactive strontium-90 – this is a stable isotope. Non-sensitizing. Pregnancy and lactation – use with caution. Direct pregnancy data are limited and manufacturers label as 'not for pregnancy'. For gestational itch the agents of choice are low-concentration menthol, colloidal oat baths, adenosine.
Frequently asked questions
Is Strontium Chloride safe during pregnancy?
Strontium Chloride should be used with caution during pregnancy. Consulting a dermatologist or OB-GYN is advisable.
What skin types is Strontium Chloride for?
Strontium Chloride suits: sensitive, normal.
What is Strontium Chloride and what does it do in cosmetics?
Strontium salt that selectively suppresses sensory C-fiber activity in skin.
What's the INCI name for Strontium Chloride?
The INCI name is Strontium Chloride.
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