Alanyl Glutamine
A dipeptide of the amino acids alanine and glutamine. It supports skin hydration and comfort. Well tolerated.
Evidence by route
Topical application
A functional dipeptide. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Alanyl glutamine (INCI Alanyl Glutamine) is a dipeptide of two amino acids, alanine and glutamine. In a formula it works as a moisturising and conditioning ingredient: it supports the water balance of the stratum corneum and helps the skin feel more comfortable. Amino acids are part of the skin's natural moisturising factor, so such peptides are familiar to it. On efficacy this is a supporting moisturising ingredient. It provides basic comfort and softness, but should not be seen as a standalone anti-ageing active, as the evidence base is modest. Used topically the dipeptide has no systemic relevance, so it can be used during pregnancy and breastfeeding without restriction. Tolerance is good. The irritation and allergy potential is low, which suits sensitive skin. Amino acid ingredients usually cause no reaction in most people.
Frequently asked questions
Is Alanyl Glutamine safe during pregnancy?
Alanyl Glutamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Alanyl Glutamine for?
Alanyl Glutamine suits: normal, dry, combination, oily, sensitive.
What is Alanyl Glutamine and what does it do in cosmetics?
A dipeptide of the amino acids alanine and glutamine.
What's the INCI name for Alanyl Glutamine?
The INCI name is Alanyl Glutamine.
See Alanyl Glutamine in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Similar role in the formula
Explore by category
Published: · updated: