Evigrade

Glutamine

An amino acid. It supports skin hydration and comfort and is part of the natural moisturizing factor. Well tolerated.

Evidence by route

B

Topical application

A functional amino acid. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Glutamine is an amino acid found in skin as part of the natural moisturizing factor and protein metabolism. INCI: Glutamine. In cosmetics it works as a humectant and conditioning agent: it holds water and supports stratum-corneum softness and comfort. It is added to moisturizing and soothing products, often alongside other amino acids. Its standalone activity is mild; it is a supporting component rather than a lead active with a marked clinical effect. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low, suitable for sensitive skin.

Frequently asked questions

Is Glutamine safe during pregnancy?

Glutamine is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Glutamine for?

Glutamine suits: normal, dry, combination, oily, sensitive.

What is Glutamine and what does it do in cosmetics?

An amino acid.

What's the INCI name for Glutamine?

The INCI name is Glutamine. It may also appear as: L-Glutamine.

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