Ornithine HCl
An amino acid. It works as a moisturizing skin conditioner and a source of amino acids. Well tolerated.
Evidence by route
Topical application
An amino-acid conditioner. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Ornithine HCl is a salt form of the amino acid ornithine, a participant in nitrogen metabolism. INCI: Ornithine HCl. In cosmetics it works as a humectant and conditioning agent, holding water and supporting skin softness, often alongside other amino acids. Its standalone activity is mild, and topical clinical data on a marked skincare effect are limited. It is a supporting component of the natural moisturizing factor rather than a lead active. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low, suitable for sensitive skin.
Frequently asked questions
Is Ornithine HCl safe during pregnancy?
Ornithine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Ornithine HCl for?
Ornithine HCl suits: normal, dry, combination, oily, sensitive.
What is Ornithine HCl and what does it do in cosmetics?
An amino acid.
What's the INCI name for Ornithine HCl?
The INCI name is Ornithine HCl. It may also appear as: Ornithine Hydrochloride.
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