Arginine HCl
A salt of the amino acid arginine. It supports hydration and joins a recovery complex. Well tolerated.
Evidence by route
Topical application
An amino acid that supports hydration. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Arginine HCl is a salt form of the amino acid arginine. INCI: Arginine HCl. In a formula it works as a humectant, conditioning agent, and part of the natural moisturizing factor. Free arginine also adjusts formula pH because it is alkaline, but in the hydrochloride form that effect is milder. It holds water and supports skin softness and comfort. Its standalone activity is mild; it is a supporting component rather than a lead active. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low, suitable for sensitive skin.
Frequently asked questions
Is Arginine HCl safe during pregnancy?
Arginine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Arginine HCl for?
Arginine HCl suits: normal, dry, combination, oily, sensitive.
What is Arginine HCl and what does it do in cosmetics?
A salt of the amino acid arginine.
What's the INCI name for Arginine HCl?
The INCI name is Arginine HCl. It may also appear as: Arginine Hydrochloride.
See Arginine HCl in a product composition right on the store page
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Similar role in the formula
Explore by category
Ingredients in the same category
Arginine PCA, Ascophyllum Nodosum Extract, Asparagine, Aspartic Acid, Dextran, Hydrogenated Jojoba Oil, Methyl Gluceth-20, Rosehip Oil
Published: · updated: