Neem leaf extract (Azadirachta indica) – an Ayurvedic ingredient with antimicrobial and anti-inflammatory action. Helps acne and irritation. Pregnancy-safe at cosmetic concentrations.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Antimicrobial and anti-inflammatory extract. Useful for acne.
Melia azadirachta leaf extract (neem) is a water-alcohol extract. INCI: Melia Azadirachta Leaf Extract. Contains azadirachtin, nimbin and quercetin. In cosmetics it is used in products for problem skin – antimicrobial action against Cutibacterium acnes is confirmed in vitro. It also has anti-inflammatory properties. Use levels run from 0.5 to 3%. Pregnancy safety. Skin absorption into the systemic circulation is minimal. Oral use during pregnancy is contraindicated (risk of miscarriage at traditional doses). Skin profile. Low irritation potential. Low allergen risk. Non-comedogenic. Suitable for oily and problem skin. Moderate evidence (B) – in vitro and small clinical data on acne.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
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Melia Azadirachta Leaf Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Melia Azadirachta Leaf Extract suits: normal, combination, oily.
Neem leaf extract (Azadirachta indica) – an Ayurvedic ingredient with antimicrobial and anti-inflammatory action.
On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
The INCI name is Melia Azadirachta Leaf Extract. It may also appear as: Neem Leaf Extract, Azadirachta Indica Leaf Extract, экстракт нима.
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