Melia Azadirachta Leaf Extract
Neem leaf extract (Azadirachta indica) – an Ayurvedic ingredient with antimicrobial and anti-inflammatory action. Helps acne and irritation. Pregnancy-safe at cosmetic concentrations.
Evidence by route
Topical application
Antimicrobial and anti-inflammatory extract. Useful for acne.
- Subapriya R, Nagini S. Medicinal properties of neem leaves. Curr Med Chem Anticancer Agents 2005. PMID 15777222
- Wylie MR, Merrell DS. Antimicrobial action of neem on Cutibacterium acnes. Pharmaceuticals 2022. PMID 35712721
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Combination, Oily
About this ingredient
Melia azadirachta leaf extract (neem) is a water-alcohol extract. INCI: Melia Azadirachta Leaf Extract. Contains azadirachtin, nimbin and quercetin. In cosmetics it is used in products for problem skin – antimicrobial action against Cutibacterium acnes is confirmed in vitro. It also has anti-inflammatory properties. Use levels run from 0.5 to 3%. Pregnancy safety. Skin absorption into the systemic circulation is minimal. Oral use during pregnancy is contraindicated (risk of miscarriage at traditional doses). Skin profile. Low irritation potential. Low allergen risk. Non-comedogenic. Suitable for oily and problem skin. Moderate evidence (B) – in vitro and small clinical data on acne.
Frequently asked questions
Is Melia Azadirachta Leaf Extract safe during pregnancy?
Melia Azadirachta Leaf Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Melia Azadirachta Leaf Extract for?
Melia Azadirachta Leaf Extract suits: normal, combination, oily.
What is Melia Azadirachta Leaf Extract and what does it do in cosmetics?
Neem leaf extract (Azadirachta indica) – an Ayurvedic ingredient with antimicrobial and anti-inflammatory action.
Is Melia Azadirachta Leaf Extract comedogenic?
On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.
What's the INCI name for Melia Azadirachta Leaf Extract?
The INCI name is Melia Azadirachta Leaf Extract. It may also appear as: Neem Leaf Extract, Azadirachta Indica Leaf Extract.
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