An amino acid from collagen. It draws water and supports skin softness. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A functional humectant amino acid. Safe.
Hydroxyproline is an amino acid, one of the key building blocks of collagen. INCI: Hydroxyproline. In cosmetics it works as a humectant and conditioning agent, holding water and supporting skin softness. Marketing often links hydroxyproline to collagen synthesis, but that should be read carefully: hydroxyproline is part of collagen inside the skin, yet an amino acid applied on the surface does not integrate directly into dermal collagen and does not build it on its own. Its real role in a formula is conditioning and moisturizing, not structural. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low, suitable for sensitive skin.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Hydroxyproline is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Hydroxyproline suits: normal, dry, combination, oily, sensitive.
An amino acid from collagen.
The INCI name is Hydroxyproline. It may also appear as: Гидроксипролин.
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