Evigrade

Lactococcus Ferment Lysate

Postbiotic ingredient – lysate of a fermented Lactococcus culture. Positioned as skin microbiome support; clinical evidence is limited.

Evidence by route

D

Topical application

Marketing postbiotic. The 'microbiome support' mechanism needs further study; no major clinical work exists.

How to read tiers A–F
  • DNo data, or very weak or conflicting data

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Sensitive, Combination

About this ingredient

Lactococcus Ferment Lysate is a postbiotic ingredient: cultivated Lactococcus lactis lactic acid bacteria disrupted by ultrasound or enzymes. Inside – cellular peptides, DNA fragments and metabolites. Mechanism. In keratinocyte culture the lysate reduces NF-κB expression and pro-inflammatory cytokines (Roudsari 2015). Claimed effect – skin microbiome support and reduced reactivity in dysbiosis. Where applied. K-beauty recovery lines (Aestura Atobarrier, Manyo Factory Galactomy), select European sensitive lines. Concentrations 0.5–3%. Evidence base. Clinical data are limited: small pilot studies in 20–40 atopy patients showed moderate barrier improvement over 4–8 weeks. Dermatology guidelines do not include this ingredient. Pregnancy and lactation – safe by composition (no live microorganisms), but direct clinical data in pregnancy are absent.

Frequently asked questions

Is Lactococcus Ferment Lysate safe during pregnancy?

Lactococcus Ferment Lysate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Lactococcus Ferment Lysate for?

Lactococcus Ferment Lysate suits: normal, dry, sensitive, combination.

What is Lactococcus Ferment Lysate and what does it do in cosmetics?

Postbiotic ingredient – lysate of a fermented Lactococcus culture.

What's the INCI name for Lactococcus Ferment Lysate?

The INCI name is Lactococcus Ferment Lysate. It may also appear as: Lactococcus Lactis Ferment Lysate.

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