Acetyl Tetrapeptide-15
A synthetic peptide. The maker links it to reduced skin sensitivity; independent data are limited. Well tolerated.
Evidence by route
Topical application
A peptide. Well tolerated; independent data limited.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Acetyl Tetrapeptide-15 (INCI: Acetyl Tetrapeptide-15) is a synthetic peptide of four amino acids with an acetyl group. The manufacturer links it to reduced skin reactivity, with the idea of modulating the signals that drive a feeling of discomfort or itch. It appears in serums and creams for sensitive skin. On efficacy, caution is in order. Independent evidence is scarce and most data come from the supplier, so it is better seen as a promising supporting active rather than a proven treatment. It may add comfort within a good formula, with no guarantee of a strong effect on its own. For topical use it has no systemic relevance and can be used during pregnancy and breastfeeding. Tolerance is good: low irritation potential and low allergy risk, suitable for sensitive skin, which is its target audience.
Frequently asked questions
Is Acetyl Tetrapeptide-15 safe during pregnancy?
Acetyl Tetrapeptide-15 is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Acetyl Tetrapeptide-15 for?
Acetyl Tetrapeptide-15 suits: normal, dry, combination, oily, sensitive.
What is Acetyl Tetrapeptide-15 and what does it do in cosmetics?
A synthetic peptide.
What's the INCI name for Acetyl Tetrapeptide-15?
The INCI name is Acetyl Tetrapeptide-15.
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