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Ceramide NG

A bioidentical ceramide from the non-hydroxylated class. One of the main lipids of the stratum corneum – restores the barrier and lowers TEWL. Pregnancy-safe.

Evidence by route

A

Topical application

Bioidentical ceramide with strong evidence for barrier restoration and atopic dermatitis.

  • Spada F et al. Skin hydration is significantly increased by a cream formulated to mimic the skin's own natural moisturizing systems. Clin Cosmet Investig Dermatol 2018. PMID 30410378
  • Chamlin SL et al. Ceramide-dominant barrier repair lipids alleviate childhood atopic dermatitis. J Am Acad Dermatol 2002;47:198-208. PMID 12140465
How to read tiers A–F
  • AProven efficacy. Two or more independent RCTs with instrumental endpoints

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Ceramide NG is a synthetic bioidentical ceramide from the non-hydroxylated class (in the new nomenclature Ceramide NG, formerly Ceramide 2). INCI: Ceramide NG. It is structurally identical to a ceramide of the human stratum corneum. In cosmetics it works as a key component of lipid-restoring formulas. The skin barrier is built on lamellar lipids, where ceramides account for about 50%. When the barrier is disrupted (atopic dermatitis, rosacea, post-procedure state) ceramide levels drop by 30-70%. Topical bioidentical ceramides restore the lamellar structure. Used in creams for dry and atopic skin, post-procedure products and anti-aging formulas. Use levels run from 0.05 to 2%. Often paired with cholesterol and fatty acids in a 1:1:1 ratio. Pregnancy safety. Skin absorption into the systemic circulation is minimal. Bioidentical to the endogenous lipid – safe. Skin profile. Very low irritation and allergen potential. Non-comedogenic. Suitable for all skin types. Active effect confirmed at level A – RCTs show barrier improvement, TEWL reduction and improvement of atopic dermatitis.

Frequently asked questions

Is Ceramide NG safe during pregnancy?

Ceramide NG is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Ceramide NG for?

Ceramide NG suits: normal, dry, combination, oily, sensitive.

What is Ceramide NG and what does it do in cosmetics?

A bioidentical ceramide from the non-hydroxylated class.

Is Ceramide NG comedogenic?

On the Fulton scale 0/5 – non-comedogenic. For acne-prone skin, a rating of 3 or higher suggests choosing an alternative.

What's the INCI name for Ceramide NG?

The INCI name is Ceramide NG. It may also appear as: Ceramide 2, N-Stearoyl Phytosphingosine.

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