An osmolyte humectant. It helps skin hold water and calm discomfort. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
A hydrating soothing ingredient. Safe.
Homarine HCl (INCI: Homarine HCl) is an osmolyte that works as a humectant. Osmolytes help cells balance their water content, so in the skin they support water retention and ease the feeling of discomfort and tightness. It appears in creams, serums and formulas for sensitive or dehydrated skin. On efficacy it is a supporting hydrating and soothing active. It improves water retention and skin comfort, with a plausible mechanism, though independent evidence is still limited. It works well as part of a moisturizing system rather than as an isolated star active. For topical use it has no systemic relevance and can be used during pregnancy and breastfeeding. Tolerance is good: low irritation potential and low allergy risk, which makes it suitable for sensitive and reactive skin, which is exactly where it is most often used.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Homarine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Homarine HCl suits: normal, dry, combination, oily, sensitive.
An osmolyte humectant.
The INCI name is Homarine HCl. It may also appear as: Гомарин гидрохлорид.
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