Evigrade

Disodium Acetyl Glucosamine Phosphate

A glucosamine derivative. It draws water and helps even the skin tone. Well tolerated.

Evidence by route

B

Topical application

A hydrating brightening ingredient. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Disodium Acetyl Glucosamine Phosphate (INCI: Disodium Acetyl Glucosamine Phosphate) is a phosphate derivative of glucosamine. In cosmetics it is used for its humectant effect and for its interest in supporting a more even skin tone. It appears in serums, creams and hydration or brightening formulas. On efficacy it sits between a humectant and a supporting active. Glucosamine is a precursor of hyaluronic acid and takes part in melanin synthesis, which gives a plausible basis for its uses. Still, the evidence for a clear brightening effect at cosmetic concentrations is modest, so it is best seen as support rather than a main treatment for dark spots. For topical use it has no systemic relevance and can be used during pregnancy and breastfeeding. Tolerance is good: low irritation potential and low allergy risk, suitable for sensitive skin.

Frequently asked questions

Is Disodium Acetyl Glucosamine Phosphate safe during pregnancy?

Disodium Acetyl Glucosamine Phosphate is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Disodium Acetyl Glucosamine Phosphate for?

Disodium Acetyl Glucosamine Phosphate suits: normal, dry, combination, oily, sensitive.

What is Disodium Acetyl Glucosamine Phosphate and what does it do in cosmetics?

A glucosamine derivative.

What's the INCI name for Disodium Acetyl Glucosamine Phosphate?

The INCI name is Disodium Acetyl Glucosamine Phosphate.

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Similar role in the formula

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Moisturizing, Brightening

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