Glucosamine HCl
An amino sugar, a precursor of hyaluronic acid. It helps retain water and even tone. Well tolerated.
Evidence by route
Topical application
An amino-sugar humectant. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Glucosamine HCl is an amino sugar, a precursor of hyaluronic acid and skin glycosaminoglycans. INCI: Glucosamine HCl. In a formula it works as a humectant and conditioning agent, and as a mild brightening component: glucosamine takes part in inhibiting tyrosinase, the enzyme of melanin synthesis. The brightening potential is better studied for the related form N-acetylglucosamine, especially paired with niacinamide for post-inflammatory pigmentation. For glucosamine HCl itself the role is more supporting and moisturizing. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.
Frequently asked questions
Is Glucosamine HCl safe during pregnancy?
Glucosamine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Glucosamine HCl for?
Glucosamine HCl suits: normal, dry, combination, oily, sensitive.
What is Glucosamine HCl and what does it do in cosmetics?
An amino sugar, a precursor of hyaluronic acid.
What's the INCI name for Glucosamine HCl?
The INCI name is Glucosamine HCl. It may also appear as: Glucosamine Hydrochloride.
See Glucosamine HCl in a product composition right on the store page
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Ingredients in the same category
Glucose, Glucuronic Acid, Glutamic Acid, Glutamine, Hydroxyproline, PEG/PPG/Polybutylene Glycol-8/5/3 Glycerin, Tetradecane, C20-22 Alcohols
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