Evigrade

Gynostemma Pentaphyllum Leaf/Stem Extract

A gynostemma extract with saponins. It soothes and supports the skin's antioxidant defense. Well tolerated.

Evidence by route

B

Topical application

A soothing antioxidant extract. Safe.

  • CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
  • BLimited evidence. One RCT or several controlled studies with limitations

Tolerability and safety

Irritation potential
Low
Allergen risk
Low
Pregnancy
Safe
Suitable for
Normal, Dry, Combination, Oily, Sensitive

About this ingredient

Gynostemma or jiaogulan extract (INCI: Gynostemma Pentaphyllum Leaf/Stem Extract) comes from an Asian plant rich in saponins called gypenosides. In cosmetics it is added to serums and creams for its supporting soothing and antioxidant action. As an active it is a supporting component. The plant has a tradition of internal use and interesting lab data, but clinical evidence for its topical effects on wrinkles or firmness is limited. It can add to a formula's antioxidant defense without being its centerpiece. Applied topically it has no meaningful systemic absorption, so its cosmetic use during pregnancy and breastfeeding is not a problem. Tolerance is good, with low irritation and allergy risk, suitable for sensitive skin. Like any plant extract, very reactive skin could respond occasionally, though that is uncommon.

Frequently asked questions

Is Gynostemma Pentaphyllum Leaf/Stem Extract safe during pregnancy?

Gynostemma Pentaphyllum Leaf/Stem Extract is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.

What skin types is Gynostemma Pentaphyllum Leaf/Stem Extract for?

Gynostemma Pentaphyllum Leaf/Stem Extract suits: normal, dry, combination, oily, sensitive.

What is Gynostemma Pentaphyllum Leaf/Stem Extract and what does it do in cosmetics?

A gynostemma extract with saponins.

What's the INCI name for Gynostemma Pentaphyllum Leaf/Stem Extract?

The INCI name is Gynostemma Pentaphyllum Leaf/Stem Extract. It may also appear as: Jiaogulan Extract, Gynostemma Pentaphyllum Extract.

See Gynostemma Pentaphyllum Leaf/Stem Extract in a product composition right on the store page

The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.

Install the extension for free

Similar role in the formula

Explore by category

Soothing, Anti-aging

Published: · updated: