Phytosphingosine HCl
A salt form of phytosphingosine, a ceramide-precursor lipid. It helps rebuild the barrier and calm skin. Well tolerated.
Evidence by route
Topical application
A barrier-restoring lipid. Safe.
- CIR Cosmetic Ingredient Review safety assessment
How to read tiers A–F
- BLimited evidence. One RCT or several controlled studies with limitations
Tolerability and safety
- Irritation potential
- Low
- Allergen risk
- Low
- Pregnancy
- Safe
- Suitable for
- Normal, Dry, Combination, Oily, Sensitive
About this ingredient
Phytosphingosine HCl is the salt form of phytosphingosine, a sphingolipid that acts as a precursor to the skin's own ceramides. It appears in low concentrations in creams and serums aimed at barrier support. On efficacy: a functional ingredient with a reasonable biological rationale. Phytosphingosine feeds into ceramide synthesis and has a mild calming profile, so in barrier-repair products it gives real but modest support, weaker than finished ceramides. On its own it won't deliver a dramatic effect; it works as part of a lipid system rather than a standalone active. During pregnancy and breastfeeding topical use is fine. Systemic absorption is negligible. Tolerance is high, with low irritation and allergy potential. Suitable for sensitive and reactive skin. Not comedogenic at typical use levels.
Frequently asked questions
Is Phytosphingosine HCl safe during pregnancy?
Phytosphingosine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
What skin types is Phytosphingosine HCl for?
Phytosphingosine HCl suits: normal, dry, combination, oily, sensitive.
What is Phytosphingosine HCl and what does it do in cosmetics?
A salt form of phytosphingosine, a ceramide-precursor lipid.
What's the INCI name for Phytosphingosine HCl?
The INCI name is Phytosphingosine HCl. It may also appear as: Phytosphingosine Hydrochloride.
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Phytosqualane, Phytosterols, Plukenetia Volubilis Seed Oil, Sea Buckthorn Oil, Sphingomonas Ferment Extract, Brassica Campestris Sterols, Ethyl Linoleate, Linoleic Acid
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