A form of vitamin B6. It joins a cofactor complex to support skin. Well tolerated.
Topical application
BLimited evidence. One RCT or several controlled studies with limitations.
Vitamin B6, a cofactor. Safe.
Pyridoxine HCl is a salt form of vitamin B6. INCI: Pyridoxine HCl. In cosmetics it works as a conditioning component, sometimes linked to oily-skin control. Vitamin B6 matters for metabolism when taken orally, but in skincare the topic is topical use, which is a different context. Topical clinical data that pyridoxine in a cream notably affects sebum or skin condition are limited, so it is a supporting component rather than a lead active with a proven effect. Pregnancy safety. Topical use, low systemic absorption, no evidence of harm. It can be used during pregnancy and lactation. Tolerance. Irritation and allergen potential are low.
Irritation potential
LowAllergen risk
LowPregnancy
SafeSuitable for
The Evigrade extension adds an evidence panel to iHerb, Sephora, Druni and 12 more stores. This ingredient and every other one in the product show evidence-tier, allergen risk and pregnancy/lactation flags at a glance.
Pyridoxine HCl is considered safe during pregnancy at typical cosmetic concentrations. Systemic absorption through the skin is minimal.
Pyridoxine HCl suits: normal, dry, combination, oily, sensitive.
A form of vitamin B6.
The INCI name is Pyridoxine HCl. It may also appear as: Пиридоксин гидрохлорид, Витамин B6, Vitamin B6.
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